Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in Canada
30 open options
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 159 sites
- TRIALNARECRUITING
Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease
transcranial direct current stimulation and naming training — 1 site
- TRIALPHASE3RECRUITING
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
No Intervention — 212 sites
- TRIALPHASE3RECRUITING
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
KarXT · KarX-EC · KarXT + KarX-EC Arm Matching Placebo — 22 sites
- TRIALNARECRUITING
Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation
tDCS and Cognitive Training — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease
ARO-MAPT-SC · Placebo — 3 sites
- TRIALNARECRUITING
Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)
Active tPBM device · Sham device — 1 site
- TRIALPHASE2 / PHASE3RECRUITING
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug (SC) · Matching Placebo (Remternetug) — 37 sites
- TRIALPHASE2 / PHASE3RECRUITING
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug · Matching Placebo (Remternetug) — 37 sites
- TRIALNARECRUITING
Longitudinal Study Examining At-Home tDCS
Transcranial Direct Current Stimulation — 1 site
- TRIALNANOT_YET_RECRUITING
CPAP Randomized Controlled Trial
CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health · Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health — 1 site
- TRIALNARECRUITING
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
In-laboratory polysomnography · Home Sleep Apnea Test — 1 site
- TRIALPHASE2NOT_YET_RECRUITING
Evaluation of the Safety and Efficacy of NeuroEPO in Subjects With Mild to Moderate Alzheimer's Disease
NeuroEPO · Placebo — 1 site
- TRIALNARECRUITING
Evaluating the Feasibility of elleFA App Implementation
Implementation of elleFA smartphone application — 1 site
- TRIALNARECRUITING
rTMS for Apathy Clinical Trial
rTMS · methylphenidate — 1 site
- TRIALNARECRUITING
Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden
PET — 1 site
- TRIALNARECRUITING
Deep rTMS for Mild Neurocognitive Disorder in Older Adults
Brainsway H1-Coil Deep TMS System · Brainsway H4-Coil Deep TMS System · Brainsway H7-Coil Deep TMS System — 1 site
- TRIALPHASE1RECRUITING
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)
RO7812653 · Placebo — 12 sites
- TRIALNARECRUITING
Nature-based Virtual Reality Intervention for Depression in Alzheimer's Disease
nature-based virtual reality applications and videos · nature-based videos — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
SNK01 · Placebo — 8 sites
- TRIALPHASE1RECRUITING
A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease
ALN-5288 · Placebo — 13 sites
- TRIALPHASE3RECRUITING
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
KarXT · Placebo — 154 sites
- TRIALNARECRUITING
Effect of Accelerated Neuromodulation of Anterior Cingulate Cortex to Enhance Cognition in Older Adults With Mild Memory Problems
Active Brainsway H7-Coil Deep TMS System · Sham Brainsway H1-Coil Deep TMS System — 1 site
- TRIALPHASE2RECRUITING
Daridorexant for Alzheimer Disease Prevention
Daridorexant 50 mg · Placebo — 1 site
- TRIALNARECRUITING
Spatial Memory Training and Cognitive Function
SMIP · No intervention — 1 site
- TRIALNARECRUITING
Deep Brain Stimulation of the Pedunculopontine Nucleus for Alzheimer's Disease
Deep Brain Stimulation of the Pedunculopontine Nucleus — 1 site
- TRIALPHASE3RECRUITING
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Acoramidis · Placebo oral tablet — 104 sites
- TRIALNARECRUITING
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
Computerized speed-based cognitive training · Computerized executive function cognitive training — 1 site
- TRIALNARECRUITING
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers — 1 site
- TRIALPHASE2RECRUITING
Open-label Extension Study in Participants With Early Alzheimer's Disease
GSK4527226 — 33 sites
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