Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — frontier options in Massachusetts
30 open options
- TRIALNANOT_YET_RECRUITING
Making Connections Thru Music
Volunteer Led Making Connections Thru Music · Staff Led Making Connections Thru Music — 1 site
- TRIALPHASE2RECRUITING
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
ITI-1284 · Placebo — 70 sites
- TRIALNARECRUITING
TMS for Cognitive Decline in Aging and Preclinical AD
Active rTMS · Sham rTMS — 1 site
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 159 sites
- TRIALPHASE1 / PHASE2RECRUITING
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Placebo (Study Part 1a) · ACI-24.060 at Dose A in Study Part 1a · ACI-24.060 at Dose B in Study Part 1a — 26 sites
- TRIALNANOT_YET_RECRUITING
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
Feeling of Being · Health Enhancement Program — 1 site
- TRIALNARECRUITING
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active) · Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham) · Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham) — 1 site
- TRIALPHASE3RECRUITING
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
No Intervention — 212 sites
- TRIALPHASE1 / PHASE2RECRUITING
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
ABBV-1758 · Placebo for ABBV-1758 · ABBV-1758 — 12 sites
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 145 sites
- TRIALPHASE2RECRUITING
Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type
12 cm2 - 2 Active DMTS Patches · 6 cm2 - 1 Active and 1 Placebo DMTS Patches · Placebo - 2 Placebo DMTS Patches — 8 sites
- TRIALNARECRUITING
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
MBCT+w · ALED — 1 site
- TRIALEARLY_PHASE1RECRUITING
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Active rTMS · Sham rTMS — 1 site
- TRIALPHASE3RECRUITING
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Donanemab · Placebo — 59 sites
- TRIALNARECRUITING
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Metronome — 1 site
- TRIALPHASE1NOT_YET_RECRUITING
NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome
MIB-626 · Placebo — 2 sites
- TRIALNARECRUITING
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
tACS device — 1 site
- TRIALNARECRUITING
Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
High definition transcranial electrical current stimulation — 1 site
- TRIALNARECRUITING
Gamma Frequency Stimulation in Individuals With Down Syndrome
GENUS device (Active Settings) · GENUS device (Sham Settings) — 1 site
- TRIALNARECRUITING
The BRAIN App (Phase 2 SBIR)
The BRAIN App — 1 site
- TRIALPHASE2RECRUITING
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
LHP588 · LHP588 · Placebo Drug — 40 sites
- TRIALPHASE2RECRUITING
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
BMS-986368 · Placebo — 75 sites
- TRIALPHASE2RECRUITING
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
GENUS · Tactile GENUS — 1 site
- TRIALPHASE1RECRUITING
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
LY3954068 · Placebo · Flortaucipir F18 — 10 sites
- TRIALPHASE3RECRUITING
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Acoramidis · Placebo oral tablet — 104 sites
- TRIALPHASE3RECRUITING
[18F]PI-2620 Phase 3 Histopathological Study
[18F]PI-2620 — 25 sites
- TRIALNAENROLLING_BY_INVITATION
Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
Sensory Stimulation System (GS120) - Active — 53 sites
- TRIALNARECRUITING
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
TRAIN AD 2.0 — 1 site
- TRIALNARECRUITING
Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease
GENUS — 2 sites
- TRIALNARECRUITING
Gamma-Music Based Intervention for Mild Alzheimer's Disease
Gamma-Music Based Intervention — 1 site
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