Eligibility map · free · live registry data

Every frontier option the patient plausibly meets.

Interventional trials and expanded-access programs, queried live from ClinicalTrials.gov against the profile you enter. Each published criterion comes back as matched, not matched, or honestly unknown — never guessed. Only the trial site can determine actual eligibility.

20 options shownof 543 open studies found

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TRIALPHASE1 / PHASE2RECRUITING

A Phase 2 Study of HX301 in Patients with High-grade Giloma

NCT06703255 · Hangzhou Hanx Biopharmaceuticals, Ltd.

HX301+/Temozolomide

Study open to new participants: Matched

Nearest sites (1 listed)

Beijing Tiantan Hospital Capital Medical University, Beijing, Beijing Municipality · RECRUITING

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TRIALPHASE1ENROLLING_BY_INVITATION

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

NCT06896110 · Andrew P. Groves

Nivolumab · Azacitidine (AZA) · lumbar puncture · MRI Contrast

Study open to new participants: Matched

Nearest sites (1 listed)

Holden Comprehensive Cancer Center, Iowa City, Iowa

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TRIALPHASE2RECRUITING

Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma

NCT07511725 · Second Affiliated Hospital, Zhejiang University, School of Medicine

Maximal surgical resection · Concomitant Chemoradiotherapy (Stupp backbone) · Preventive Intrathecal Thiotepa

Study open to new participants: Matched

Nearest sites (1 listed)

2nd Affiliated Hospital, School of Medicine, Hangzhou, Zhejiang · RECRUITING

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TRIALNANOT_YET_RECRUITING

Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors.

NCT07029100 · Centre Henri Becquerel

Ex-vivo organoid culture

Study open to new participants: Matched

Nearest sites (3 listed)

Groupe Hospitalier du Havre, Le Havre
Centre Henri Becquerel, Rouen
CHU Rouen, Rouen

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TRIALPHASE3RECRUITING

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NCT06496971 · NaviFUS Corporation

Bevacizumab · Microbubble · Low-Intensity Focused Ultrasound

Study open to new participants: Matched

Nearest sites (2 listed)

National Taiwan University Hospital, Taipei · RECRUITING
Linkou Chang Gung Memorial Hospital, Taoyuan · RECRUITING

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TRIALPHASE1 / PHASE2RECRUITING

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

NCT04977375 · Chirag G. Patil

Pembrolizumab · Stereotactic Radiation Therapy · Surgical Resection

Study open to new participants: Matched

Nearest sites (1 listed)

Cedars-Sinai Medical Center, Los Angeles, California · RECRUITING

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TRIALPHASE1 / PHASE2RECRUITING

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

NCT05765812 · Debiopharm International SA

Debio 0123 · Temozolomide · Radiotherapy

Study open to new participants: Matched

Nearest sites (16 listed)

Northwestern Memorial Hospital, Chicago, Illinois · RECRUITING
New York University Langone Medical Center, New York, New York · RECRUITING
David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York, New York · RECRUITING

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EXPANDED ACCESSAVAILABLE

Glioblastoma and Individualized Therapies

NCT05356312 · Zentrum fur Humangenetik Tuebingen

Vaccination

Study open to new participants: Matched

Nearest sites (1 listed)

Zentrum für Humangenetik Tübingen, Tübingen · AVAILABLE

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TRIALPHASE1 / PHASE2RECRUITING

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

NCT07468136 · Mayo Clinic

Biospecimen Collection · Eflornithine · Lumbar Puncture · Magnetic Resonance Imaging

Study open to new participants: Matched

Nearest sites (1 listed)

Mayo Clinic in Rochester, Rochester, Minnesota · RECRUITING

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TRIALPHASE2RECRUITING

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

NCT06838676 · Nationwide Children's Hospital

ACT001

Study open to new participants: Matched

Nearest sites (20 listed)

Children's Hospital Colorado, Aurora, Colorado · RECRUITING
Children's National Medical Center, Washington D.C., District of Columbia · RECRUITING
Nicklaus Children's Hospital, Miami, Florida · NOT_YET_RECRUITING

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TRIALEARLY_PHASE1RECRUITING

Pilot Trial for Treatment of Recurrent Glioblastoma

NCT05432518 · AHS Cancer Control Alberta

Afatinib · Dasatinib · Palbociclib · Everolimus

Study open to new participants: Matched

Nearest sites (1 listed)

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta · RECRUITING

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TRIALNARECRUITING

Assessment of Early Post-operative Nuclear Imaging in Neurosurgery: a Safety and Feasibility Study in Patients Operated for Glioblastoma

NCT07274397 · Beta Emitting Accurate Monitored Systems

Early post-operative brain PET-MRI with 18F-DOPA and Gadolinium

Study open to new participants: Matched

Nearest sites (1 listed)

Hôpital Henri Mondor - Université Paris-Est Créteil (UPEC), Créteil · RECRUITING

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TRIALPHASE2RECRUITING

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

NCT02977780 · David Reardon, MD

Temozolomide · Neratinib · QBS10072S · Abemaciclib

Study open to new participants: Matched

Nearest sites (12 listed)

University of Alabama at Birmingham, Birmingham, Alabama · ACTIVE_NOT_RECRUITING
Massachusetts General Hospital, Boston, Massachusetts · RECRUITING
Dana Farber Cancer Institute, Boston, Massachusetts · RECRUITING

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TRIALPHASE1 / PHASE2RECRUITING

Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors

NCT07523529 · Beijing Biotech

Autologous dual-target CAR-T cells selected from the predefined target library. · Fludarabine · Cyclophosphamide

Study open to new participants: Matched

Nearest sites (1 listed)

Peking University Shenzhen Hospital, Shenzhen, Guangdong · RECRUITING

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TRIALPHASE1 / PHASE2RECRUITING

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

NCT06712875 · Ann & Robert H Lurie Children's Hospital of Chicago

Trametinib and Nivolumab · Dabrafenib, trametinib, nivolumab

Study open to new participants: Matched

Nearest sites (3 listed)

Children's National Hospital, Washington D.C., District of Columbia · NOT_YET_RECRUITING
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois · RECRUITING
Memorial Sloan Kettering Cancer Center, New York, New York · NOT_YET_RECRUITING

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TRIALPHASE1 / PHASE2RECRUITING

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

NCT06810544 · Tango Therapeutics, Inc.

TNG456 · abemaciclib

Study open to new participants: Matched

Nearest sites (15 listed)

Mayo Clinic Scottsdale, Scottsdale, Arizona · RECRUITING
University of California, Irvine, Irvine, California · RECRUITING
University of California Los Angeles, Los Angeles, California · RECRUITING

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TRIALPHASE2RECRUITING

Lerapolturev (PVSRIPO) in GBM

NCT06177964 · Darell Bigner

Lerapolturev · Lomustine Pill

Study open to new participants: Matched

Nearest sites (1 listed)

Duke University Medical Center, Durham, North Carolina · RECRUITING

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TRIALPHASE1RECRUITING

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

NCT06934889 · Memorial Sloan Kettering Cancer Center

ERAS-801 · ABBV-637 · ABBV-155 · Temozolomide

Study open to new participants: Matched

Nearest sites (11 listed)

University of California, Los Angeles (Data Collection Only), Los Angeles, California · RECRUITING
University of Miami (Data collection only), Miami, Florida · RECRUITING
Indiana University (Data Collection Only), Indianapolis, Indiana · RECRUITING

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TRIALPHASE1RECRUITING

Intracranial Injection of NK-92/5.28.z Cells in Combination With Intravenous Ezabenlimab in Patients With Recurrent HER2-positive Glioblastoma

NCT03383978 · Johann Wolfgang Goethe University Hospital

NK-92/5.28.z · Ezabenlimab

Study open to new participants: Matched

Nearest sites (5 listed)

Neurochirurgische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg · RECRUITING
Neurochirurgische Klinik, Universitätsmedizin Mannheim, Mannheim, Baden-Wurttemberg · RECRUITING
Neurochirurgische Klinik, Universitätsmedizin Mainz, Mainz, Rhineland-Palatinate · RECRUITING

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TRIALNARECRUITING

Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial

NCT06533163 · BioTex, Inc.

Oncomagnetic device

Study open to new participants: Matched

Nearest sites (6 listed)

Clinical Center Stuttgart, Stuttgart, Baden-Wurttemberg · RECRUITING
Technical University of Munich, München, Bavaria · RECRUITING
University Hospital Bonn, Bonn, North Rhine-Westphalia · RECRUITING

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Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Results come from Trial0’s live query of ClinicalTrials.gov and reflect what the registry publishes right now.