Trial0

Clinical trial · NCT05149742 · RECRUITING · NA

Deafness and Cognition in Middle-aged Adults

Sponsor: Assistance Publique - Hôpitaux de Paris

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Summary

A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing loss and patients with normal hearing in patients aged 45 to 64 years.

Interventions

  • Cognitive and audiometry evaluation · BEHAVIORAL

    For both Patients and controls: * Cognitive functions evaluation * Tonal and vocal audiometry * Self questionnaires

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* Cases: Patients aged between 45 to 64 years with severe to profound bilateral post-lingual sensorineural hearing loss with a maximum intelligibility of 70% (disyllabic words) in free-field silence with hearing aids at 60 dB SPL, current in french
* Controls: normal hearing subjects matched on age, sex and education level

Exclusion Criteria:

* Associated disability that prevents the tests from being performed
* Past and current history of neurological and psychiatric disorders including meningitis
* Psychotropic drug treatment
* Vulnerable subject

Sites (1)

  • Centre de Recherche en Audiologie (CReA) - Groupe Hospitalier Pitié-Salpêtrière, Paris, France · RECRUITING

Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Registry data refreshed at most hourly; last update posted 2025-09-15.