Multimodal Investigation of Neural Plasticity

Summary

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

Interventions

• sham tDCS · DEVICE

  Participants will receive sham (placebo) HD-tDCS for 20 minutes, for 1 session.

• active tDCS · DEVICE

  Participants will receive HD-tDCS at 3 milliAmp for 20 minutes, for 1 session.

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants
* Right-handedness
* Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head)

Exclusion Criteria:

* History of other contributing neurological or medical conditions known to affect cognitive functioning
* Significant mental illness
* Sensory impairments that limit ability to participate
* History of alcohol or drug abuse/dependence

Sites (1)

• University of Michigan, Ann Arbor, Michigan · RECRUITING