Personalized Education and Genetic Counseling to Increase Genetic Testing in Patients With a Known Family History of Pancreatic Cancer

Summary

This clinical trial studies whether personalized education and genetic counseling increases genetic testing in patients with a known family history of pancreatic cancer. Approximately 10% of pancreatic cancer cases are genetically linked and therefore, if a gene is found that could put a patient at risk, it could guide the patient to obtain more frequent screening for pancreatic cancer and possibly detect it earlier when it is more treatable. The current National Comprehensive Cancer Network (NCCN) guidelines suggest patients with a first-degree relative (parent, sibling, child) with pancreatic cancer be referred for a genetics consultation to discuss genetic testing if the affected family member cannot be tested. Personalized education is based on the patient's family history of pancreatic cancer and offers information regarding the current NCCN guidelines. This may be an effective method to increase patients' understanding of their pancreatic cancer risk and the NCCN guidelines. Genetic counseling is provided by an expert in hereditary disorders. The patient's family and personal medical history may be discussed, and counseling may lead to genetic testing. Personalized education and genetic counseling may increase genetic testing in patients with a known family history of pancreatic cancer.

Interventions

• Biospecimen Collection · PROCEDURE

  Undergo collection of blood or salvia samples

• Educational Intervention · OTHER

  Receive personalized EPIC message

• Electronic Health Record Review · OTHER

  Ancillary studies

• Genetic Counseling · OTHER

  Receive pre- and post-genetic test counseling

• Genetic Testing for Cancer Risk · GENETIC

  Undergo standard of care (SOC) genetic testing

• Survey Administration · OTHER

  Ancillary studies

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* First-degree relative with pancreatic cancer listed in the EPIC family history tool
* Active patient at Mayo Clinic Florida (MCF) (visits within 1/1/2023-12/31/2023 to Family Medicine and/or Gastroenterology and Hepatology)

Exclusion Criteria:

* Patients not meeting the inclusion criteria as defined above
* Patients with an active or past history of pancreatic cancer
* Patients who are pregnant or breastfeeding

Sites (1)

• Mayo Clinic in Florida, Jacksonville, Florida