Trial0

Clinical trial · NCT07040904 · RECRUITING · NA

Mindfulness to Enhance Cognitive Health in Latino Older Adults

Sponsor: Washington University School of Medicine

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Summary

The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in Latino older adults, thereby mitigating risk of Alzheimer's Disease (AD) in a population that may be particularly vulnerable.

Interventions

  • mindfulness · BEHAVIORAL

    MBSR: Mindfulness Program A novel and culturally-adapted version of the well-validated mindfulness-based stress reduction (MBSR) course will be used for the intervention. The adapted program curriculum embeds core MBSR principles and practices within a culturally responsive didactic framework developed directly from community focus-group feedback. The course will be delivered via a group meeting across 8 weeks, with weekly classes held at a local community center. All classes will be held in hybrid format, with most participants attending in person, but with a live-stream option offered via Zoom.

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* Hispanic/Latino
* Age 65 and older
* Male, female, or non-binary
* Community living
* Medically stable and willing to undergo the study procedures
* No extensive mindfulness training experience

Exclusion Criteria:

* Clinically unstable psychiatric disorder that requires immediate treatment (e.g., ECT)
* Medical conditions suggesting significantly shortened lifespan (e.g., metastatic cancer) or prohibiting safe participation in the interventions/assessments (e.g., Parkinson's disease, musculoskeletal conditions)
* Sensory impairment (hearing, vision) preventing participation
* Current alcohol or substance abuse
* Current/concurrent cognitive training known to affect neuroplasticity (e.g., brain-training programs), or other interventions expected to affect neuroplasticity significantly (e.g., psychedelics, cholinesterase inhibitors, high-dose sedatives).

Sites (1)

  • Washington University, St Louis, Missouri · RECRUITING

Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Registry data refreshed at most hourly; last update posted 2026-05-11.