Trial0

Clinical trial · NCT07296133 · RECRUITING · NA

GAMES Intervention in MCI (Mild Cognitive Impairment)

Sponsor: Emory University

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Summary

The objective of the present study is to evaluate whether online, remote gameplay can facilitate social engagement and reduce feelings of loneliness and isolation in adults with and without mild cognitive impairment (MCI).

Interventions

  • Online Gameplay Intervention · BEHAVIORAL

    -The online gameplay intervention includes playing online versions of common games (such as Connect 4 and Uno) with a partner, 3 times per week for at least 15 minutes, for 12 weeks. All games will be delivered via a novel online platform (OneClick; developed by PotLuck, LLC) created specifically to support and enhance social engagement with family members and close friends. * Participants will receive weekly calls from study staff to provide support and briefly query about social activities that week. * They will not receive reminders or be contacted by the study outside of the weekly phone calls, apart from mid intervention questionnaires.

  • Waitlist control · BEHAVIORAL

    \- Participants will be informed that study team will contact them once per week by telephone for 12 weeks, to ask about social activities they completed in the week prior.

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* 50 to 85 years old
* Living independently (note: can live in assisted living, but must have independently complete daily activities)
* Fluent in English
* Adequate visual and auditory acuity to see/hear computer screen
* MoCA-Blind (converted to MoCA score) \> 17

Additional Criteria for MCI Group:

* Existing diagnosis by HC professional
* MoCA-Blind (converted to MoCA score) of 18-25
* FAQ \< 9

Exclusion Criteria:

* Cognitive impairment secondary to stroke, TBI or other neurological cause without concern for neurodegenerative condition (e.g., Alzheimer's disease, vascular dementia, etc.)
* Medical illnesses that would prevent participation
* Major psychiatric disturbance meeting DSM V criteria in last year
* Hx of substance abuse within last two years
* Current psychoactive med use

Sites (1)

  • Emory University, Atlanta, Georgia · RECRUITING

Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Registry data refreshed at most hourly; last update posted 2025-12-22.