Adapting RDAD for DS

Summary

The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.

Interventions

• Remote Exercise Sessions · BEHAVIORAL

  Participants will take part in thrice weekly exercise sessions using pre-recorded videos designed for older adults with Down syndrome. Participants will join video call and follow along with the video. A staff member familiar with the population will be on the call to provide modifications, encouragement and ensure participant safety.

• Caregiver Education Sessions · BEHAVIORAL

  Caregivers will join a once-weekly education session held via video call and led by a trained staff member. Education content will include how to support and manage challenging behaviors of older adults with Down syndrome who may be experiencing Alzheimer's disease-related symptoms.

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria - Adults with Down syndrome:

* Age \>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \~31 in adults with DS.
* Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.
* Living at home or in a supported living environment with a parent/caregiver who agrees to serve as a study partner.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Adults with Down syndrome:

* Unable to participate in moderate-to-vigorous physical activity.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

Inclusion Criteria - Caregivers

* Age ≥18 yrs.
* Reports being a primary caregiver of an adult with DS.
* English speaking.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Caregivers

* Unable to participate in moderate PA, i.e., brisk walking.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

Sites (1)

• University of Kansas Medical Center, Kansas City, Kansas · RECRUITING