Trial0

Clinical trial · NCT07485712 · NOT_YET_RECRUITING · NA

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2

Sponsor: Weill Medical College of Cornell University

Summary

The goal of this Stage 1 (NIH Stage Model) Intervention Development cross-site project is to develop, using a user-centered design approach, and evaluate an innovative intelligent adaptive software package aimed at providing cognitive and social support and engagement to older adults with mild cognitive impairment (MCI). The system will be designed to adapt to the needs and abilities of the user. The investigator's goal is to develop a unique and highly innovative technology tool that can provide adaptive support to aging individuals with MCI, even as cognition might deteriorate further. Speech data collected as part of an embedded reminiscence feature will advance fundamental knowledge of how speech and language production data might serve as an early indicator of cognitive decline.

Interventions

  • Project 2, Phase 2: Intelligent Adaptive System · BEHAVIORAL

    An innovative intelligent adaptive software package aimed at providing social and cognitive support to older adults with MCI. The system will be designed to adapt to the needs and abilities of the user.

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* 62+ years of age
* Able to read English at the 6th grade level
* Have 20/60 vision with or without correction.
* Clinical diagnosis of mild cognitive impairment (MCI)
* Subjective cognitive complaints
* Evidence by clinical evaluation
* Clinical Dementia Rating Global scale of 0.5-2.0
* Probable MCI
* Montreal Cognitive Assessment (MoCA) score of 18-26
* No major Instrumental activities of daily living (IADL) impairments
* Geriatric Depression Scale of 4 or Below
* No diagnosis of dementia

Exclusion Criteria:

* Blind or have visual impairments that limit their ability to view the technology.
* Deaf or have hearing impairments that limit their ability to answer telephone queries.
* Have a life-limiting/terminal illness
* Severe motor impairment (e.g., severe tremors or debilitating arthritis in their hands) that impairs ability to speak or use dominant hand
* Cognitive impairment (MOCA ≤ 25)

Sites (3)

  • Florida State University, Tallahassee, Florida
  • University of Illinois Urbana-Champaign, Champaign, Illinois
  • Weill Cornell Medicine, New York, New York

Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Registry data refreshed at most hourly; last update posted 2026-08-17.