Hypofractionated Radiotherapy Plus Temozolamide in Patients Younger Than 70 Years With Glioblastoma

Summary

The goal of this clinical trial is to evaluate the feasibility, safety and effectiveness of radiotherapy with fewer days of treatment and a higher dose of radiation each day in patients under 70 years of age diagnosed with a brain tumor known as glioblastoma.

Interventions

• Hypofractionated Radiation Therapy · RADIATION

  60 Gy in 20 fractions of 3 Gy

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* Initial histological diagnosis of glioblastoma
* Age \> 18 and \< 70 years;
* Karnofsky Performance Status \> 70%;
* Patient consent to participate in the study.

Exclusion Criteria:

* Patients submitted to any type of previous radiotherapy in the cranial region;
* Multicentric tumors;
* Contraindication to chemotherapy with temozolomide;
* Contraindications for performing magnetic resonance imaging (MRI), such as the use of implants or metallic prostheses;
* Pregnant women or women of childbearing age who refuse to undergo the beta-HCG test before treatment and contraception during the intervention.

Sites (0)

• The registry lists no site contacts for this record.