Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in United States
30 open options
- TRIALNANOT_YET_RECRUITING
Making Connections Thru Music
Volunteer Led Making Connections Thru Music · Staff Led Making Connections Thru Music — 1 site
- TRIALNANOT_YET_RECRUITING
Ultrasonic Debris Clearance to Promote Brain Resilience
Ultrasonic Debris Clearance · sham — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Sense4Safety Intervention
Sense4Safety — 1 site
- TRIALNARECRUITING
Evaluation of a Mobile App Program for Coping With Cancer
Tools for Coping with Cancer Calm Health mobile app program — 1 site
- TRIALPHASE2RECRUITING
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
ITI-1284 · Placebo — 70 sites
- TRIALNANOT_YET_RECRUITING
Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2
Project 2, Phase 2: Intelligent Adaptive System — 3 sites
- TRIALPHASE2RECRUITING
DORA and LP in Alzheimer's Disease Biomarkers
Lemborexant 10 mg · Lemborexant 20mg · Placebo — 1 site
- TRIALNARECRUITING
TMS for Cognitive Decline in Aging and Preclinical AD
Active rTMS · Sham rTMS — 1 site
- TRIALNARECRUITING
Neurologic Stem Cell Treatment Study
Intravenous and Intranasal BMSC — 3 sites
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 159 sites
- TRIALNARECRUITING
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
5 Sessions of Split-belt Treadmill-based Locomotor Adaptation — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Placebo (Study Part 1a) · ACI-24.060 at Dose A in Study Part 1a · ACI-24.060 at Dose B in Study Part 1a — 26 sites
- TRIALNANOT_YET_RECRUITING
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
Feeling of Being · Health Enhancement Program — 1 site
- TRIALNARECRUITING
Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial
MI MOM App — 8 sites
- TRIALNARECRUITING
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
Progressive aerobic exercise · Adaptive cognitive training · Combined — 1 site
- TRIALPHASE3RECRUITING
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
KarXT · Placebo — 129 sites
- TRIALNARECRUITING
Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
Photobiomodulation — 1 site
- TRIALNARECRUITING
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active) · Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham) · Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham) — 1 site
- TRIALPHASE4RECRUITING
Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
Gabapentin Enacarbil · Placebo Oral Tablet — 1 site
- TRIALNARECRUITING
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
Symani Surgical System — 3 sites
- TRIALEARLY_PHASE1RECRUITING
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Psilocybin — 1 site
- TRIALPHASE3RECRUITING
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
No Intervention — 212 sites
- TRIALNARECRUITING
Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
F-18 AV 1451 · C-11 PiB — 1 site
- TRIALPHASE4ENROLLING_BY_INVITATION
MIBG in Aging and Neurologic Disorders
meta-iodobenzylguanidine (MIBG) (123I) · 123I-MIBG scintigraphy — 1 site
- TRIALNARECRUITING
Early-Stage Partner in Care Living Alone Plus
Psychoeducational skills training intervention — 1 site
- TRIALNARECRUITING
Low-Intensity Focused Ultrasound (LIFU) Neuromodulation
low intensity focused ultrasound (LIFU) — 1 site
- TRIALNARECRUITING
Impact of a Biophoton Therapy on Patients With Brain Disorders
Biophotonizer - a Biophoton Generator — 1 site
- TRIALNANOT_YET_RECRUITING
Fall Prevention in Mild Cognitive Impairment
Virtual Neurophysiological Rehabilitation — 1 site
- TRIALNARECRUITING
Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI
STEM — 1 site
- TRIALPHASE2ENROLLING_BY_INVITATION
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
Couples-based treatment- Patient · Couples-based treatment- Partner · Information control- Patient — 2 sites
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