Glioblastoma — frontier options in Maryland
24 open options
- TRIALPHASE4RECRUITING
Dabrafenib and/or Trametinib Rollover Study
dabrafenib · trametinib — 33 sites
- TRIALPHASE1 / PHASE2RECRUITING
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Biopsy Procedure · Magnetic Resonance Imaging · Radiation Therapy — 127 sites
- TRIALPHASE1RECRUITING
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Everolimus · Trametinib — 17 sites
- TRIALPHASE3RECRUITING
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
SonoCloud-9 (SC9) · Carboplatin · Lomustine — 55 sites
- TRIALPHASE2NOT_YET_RECRUITING
The GLIOMAX Study: MT027 Allogeneic CAR-T for Recurrent Glioma
Intracerebroventricular injection of MT027 UCAR-T Cell targeting B7H3 — 4 sites
- TRIALPHASE2RECRUITING
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
silevertinib in combination with temozolomide · temozolomide (TMZ) — 25 sites
- TRIALPHASE1 / PHASE2RECRUITING
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
PLX038 — 1 site
- TRIALPHASE1RECRUITING
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
²¹²Pb-DOTAM-GRPR1 — 8 sites
- TRIALPHASE1 / PHASE2RECRUITING
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
LMP744 · Conventional Surgery or Biopsy — 1 site
- TRIALNARECRUITING
LITT Followed by Hypofractionated RT for Recurrent Gliomas
Procedure: LITT · Hypo-Fractionated Radiation Therapy — 4 sites
- TRIALPHASE1RECRUITING
Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma
Retifanlimab · Temozolomide · Radiation Therapy — 1 site
- TRIALPHASE2RECRUITING
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
BMS-986504 · Daraxonrasib · Nivolumab + Relatlimab FDC — 57 sites
- TRIALPHASE1RECRUITING
A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM
TheraSphere GBM — 9 sites
- TRIALPHASE1RECRUITING
Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Radiation Therapy — 1 site
- TRIALPHASE3RECRUITING
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Optune® device · Temozolomide · Pembrolizumab — 102 sites
- TRIALPHASE1 / PHASE2RECRUITING
Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas
Treatment Period 1 · Treatment Period 2 · Treatment Period 3 — 2 sites
- TRIALPHASE1 / PHASE2RECRUITING
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
Zotiraciclib — 1 site
- TRIALPHASE1RECRUITING
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
ONC206 — 1 site
- TRIALNARECRUITING
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
LITT · Hypofractionated Radiation Therapy — 5 sites
- TRIALPHASE3RECRUITING
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
GammaTile® · External Beam Radiation Therapy · Temozolomide — 7 sites
- TRIALPHASE2RECRUITING
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Plixorafenib — 70 sites
- TRIALEARLY_PHASE1NOT_YET_RECRUITING
Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas
avutometinib and defactinib for 3 weeks on/1 week off · MGMT-unmethylated GBM with Radiation — 3 sites
- TRIALNARECRUITING
Precision Radiotherapy Enabled by Molecular MRI
Amide proton transfer radiotherapy · Standard radiotherapy — 1 site
- TRIALNARECRUITING
Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)
Music intervention — 1 site
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