Glioblastoma — procedure & surgical options
19 open options
- TRIALPHASE1ENROLLING_BY_INVITATION
Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma
Nivolumab · Azacitidine (AZA) · lumbar puncture — 1 site
- TRIALPHASE2RECRUITING
Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma
Maximal surgical resection · Concomitant Chemoradiotherapy (Stupp backbone) · Preventive Intrathecal Thiotepa — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
Pembrolizumab · Stereotactic Radiation Therapy · Surgical Resection — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas
Biospecimen Collection · Eflornithine · Lumbar Puncture — 1 site
- TRIALPHASE2RECRUITING
Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma
Bevacizumab · Biospecimen Collection · Computed Tomography — 3 sites
- TRIALPHASE1RECRUITING
Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas
Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells · Biopsy Procedure · Biospecimen Collection — 1 site
- TRIALPHASE1RECRUITING
Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
Anti-GARP Chimeric Antigen Receptor-T Cells · Biospecimen Collection · Chest Radiography — 1 site
- TRIALNARECRUITING
Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
MRI and advanced MRI sequences — 1 site
- TRIALNARECRUITING
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma
Sonobiopsy · Research blood · Cancer Personalized Profiling — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
Near-Infrared Fluorescence Imaging · Panitumumab · Panitumumab-IRDye800 — 1 site
- TRIALPHASE2NOT_YET_RECRUITING
Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma
Archive Sample Retrieval · Biospecimen Collection · Chest Radiography — 3 sites
- TRIALNANOT_YET_RECRUITING
Establishing Radiolabelled PSMA as a Target for Glioma Treatment
PET-MRI · Brain tumour biopsy — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Biopsy Procedure · Magnetic Resonance Imaging · Radiation Therapy — 127 sites
- TRIALPHASE2RECRUITING
Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging · Fluciclovine F18 · Gadolinium-Chelate — 18 sites
- TRIALPHASE2RECRUITING
Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread
Intrathecal injection of thiotepa · Stupp regimen (oral temozolomide) · Radical radiotherapy — 1 site
- TRIALNANOT_YET_RECRUITING
Neuromodulation-Induced Cortical Prehabilitation in High Grade Glioma Near the Motor Pathway: Cortical Plasticity Assessed by Navigated Transcranial Magnetic Stimulation (nTMS)
Physical Therapy · Combined Therapy Group
- TRIALNARECRUITING
Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma
Best Practice · Biospecimen Collection · Dietary Intervention — 3 sites
- TRIALPHASE1RECRUITING
Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells
E-SYNC T Cells · Cyclophosphamide (non-investigational) · Fludarabine (non-investigational) — 1 site
- TRIALPHASE2RECRUITING
DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)
DOC1021 · Tumor resection · Temodar (Temozolomide) — 18 sites
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